HL7 Terminology
2.1.0 - Publication
HL7 Terminology
2.1.0 - Publication
This page is part of the HL7 Terminology (v2.1.0: Release) based on FHIR R4. The current version which supercedes this version is 5.2.0. For a full list of available versions, see the Directory of published versions 
<CodeSystem xmlns="http://hl7.org/fhir">
<id value="v3-substanceAdminSubstitution"/>
<language value="en"/>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en"><p><b>Properties</b></p><table class="grid"><tr><td><b>Code</b></td><td><b>URL</b></td><td><b>Description</b></td><td><b>Type</b></td></tr><tr><td>Specializes</td><td/><td>The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.</td><td>Coding</td></tr><tr><td>Generalizes</td><td/><td>Inverse of Specializes. Only included as a derived relationship.</td><td>Coding</td></tr><tr><td>internalId</td><td>http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id</td><td>The internal identifier for the concept in the HL7 Access database repository.</td><td>code</td></tr><tr><td>notSelectable</td><td>http://hl7.org/fhir/concept-properties#notSelectable</td><td>Indicates that the code is abstract - only intended to be used as a selector for other concepts</td><td>boolean</td></tr><tr><td>status</td><td>http://hl7.org/fhir/concept-properties#status</td><td>Designation of a concept's state. Normally is not populated unless the state is retired.</td><td>code</td></tr></table><p>This code system http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution defines the following codes:</p><table class="codes"><tr><td><b>Lvl</b></td><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>internalId</b></td><td><b>Not Selectable</b></td><td><b>status</b></td></tr><tr><td>1</td><td style="white-space:nowrap">_ActSubstanceAdminSubstitutionCode<a name="v3-substanceAdminSubstitution-_ActSubstanceAdminSubstitutionCode"> </a></td><td>ActSubstanceAdminSubstitutionCode</td><td>**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.</td><td>21284</td><td>true</td><td>active</td></tr><tr><td>2</td><td style="white-space:nowrap"> E<a name="v3-substanceAdminSubstitution-E"> </a></td><td>equivalent</td><td>**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.</td><td>23107</td><td/><td>active</td></tr><tr><td>3</td><td style="white-space:nowrap"> EC<a name="v3-substanceAdminSubstitution-EC"> </a></td><td>equivalent composition</td><td>**Description:**
Substitution occurred or is permitted with another product that is a:
* pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
* pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration
*Examples:*
* *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate
* *Pharmaceutical equivalent:* Lisonpril for Zestril</td><td>23108</td><td/><td>active</td></tr><tr><td>4</td><td style="white-space:nowrap"> BC<a name="v3-substanceAdminSubstitution-BC"> </a></td><td>brand composition</td><td>**Description:**
Substitution occurred or is permitted between equivalent Brands but not Generics
*Examples:*
* Zestril for Prinivil
* Coumadin for Jantoven</td><td>23109</td><td/><td>active</td></tr><tr><td>4</td><td style="white-space:nowrap"> G<a name="v3-substanceAdminSubstitution-G"> </a></td><td>generic composition</td><td>**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands
*Examples:*
* Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)</td><td>16623</td><td/><td>active</td></tr><tr><td>3</td><td style="white-space:nowrap"> TE<a name="v3-substanceAdminSubstitution-TE"> </a></td><td>therapeutic alternative</td><td>**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.
*Examples:*
* ranitidine for Tagamet</td><td>16624</td><td/><td>active</td></tr><tr><td>4</td><td style="white-space:nowrap"> TB<a name="v3-substanceAdminSubstitution-TB"> </a></td><td>therapeutic brand</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics
>
*Examples:*
* Zantac for Tagamet</td><td>23105</td><td/><td>active</td></tr><tr><td>4</td><td style="white-space:nowrap"> TG<a name="v3-substanceAdminSubstitution-TG"> </a></td><td>therapeutic generic</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands
>
*Examples:*
* Ranitidine for cimetidine</td><td>23106</td><td/><td>active</td></tr><tr><td>2</td><td style="white-space:nowrap"> F<a name="v3-substanceAdminSubstitution-F"> </a></td><td>formulary</td><td>**Description:** This substitution was performed or is permitted based on formulary guidelines.</td><td>16625</td><td/><td>active</td></tr><tr><td>2</td><td style="white-space:nowrap"> N<a name="v3-substanceAdminSubstitution-N"> </a></td><td>none</td><td>No substitution occurred or is permitted.</td><td>16622</td><td/><td>active</td></tr></table></div>
</text>
<url
value="http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution"/>
<identifier>
<system value="urn:ietf:rfc:3986"/>
<value value="urn:oid:2.16.840.1.113883.5.1070"/>
</identifier>
<version value="2.0.0"/>
<name value="SubstanceAdminSubstitution"/>
<title value="Substance Admin Substitution"/>
<status value="active"/>
<date value="2019-03-20"/>
<publisher value="Health Level 7"/>
<contact>
<name value="Health Level Seven"/>
</contact>
<description
value="Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided."/>
<hierarchyMeaning value="is-a"/>
<content value="complete"/>
<property>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry">
<valueCode value="antisymmetric"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity">
<valueCode value="transitive"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity">
<valueCode value="irreflexive"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable">
<valueBoolean value="true"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind">
<valueCode value="Specializes"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName">
<valueString value="Generalizes"/>
</extension>
<code value="Specializes"/>
<description
value="The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric."/>
<type value="Coding"/>
</property>
<property>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry">
<valueCode value="antisymmetric"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity">
<valueCode value="transitive"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity">
<valueCode value="irreflexive"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable">
<valueBoolean value="true"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind">
<valueCode value="Generalizes"/>
</extension>
<extension
url="http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName">
<valueString value="Specializes"/>
</extension>
<code value="Generalizes"/>
<description
value="Inverse of Specializes. Only included as a derived relationship."/>
<type value="Coding"/>
</property>
<property>
<code value="internalId"/>
<uri
value="http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id"/>
<description
value="The internal identifier for the concept in the HL7 Access database repository."/>
<type value="code"/>
</property>
<property>
<code value="notSelectable"/>
<uri value="http://hl7.org/fhir/concept-properties#notSelectable"/>
<description
value="Indicates that the code is abstract - only intended to be used as a selector for other concepts"/>
<type value="boolean"/>
</property>
<property>
<code value="status"/>
<uri value="http://hl7.org/fhir/concept-properties#status"/>
<description
value="Designation of a concept's state. Normally is not populated unless the state is retired."/>
<type value="code"/>
</property>
<concept>
<code value="_ActSubstanceAdminSubstitutionCode"/>
<display value="ActSubstanceAdminSubstitutionCode"/>
<definition
value="**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects."/>
<property>
<code value="notSelectable"/>
<valueBoolean value="true"/>
</property>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="21284"/>
</property>
<concept>
<code value="E"/>
<display value="equivalent"/>
<definition
value="**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product."/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="23107"/>
</property>
<concept>
<code value="EC"/>
<display value="equivalent composition"/>
<definition
value="**Description:**
Substitution occurred or is permitted with another product that is a:
* pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
* pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration
*Examples:*
* *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate
* *Pharmaceutical equivalent:* Lisonpril for Zestril"/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="23108"/>
</property>
<concept>
<code value="BC"/>
<display value="brand composition"/>
<definition
value="**Description:**
Substitution occurred or is permitted between equivalent Brands but not Generics
*Examples:*
* Zestril for Prinivil
* Coumadin for Jantoven"/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="23109"/>
</property>
</concept>
<concept>
<code value="G"/>
<display value="generic composition"/>
<definition
value="**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands
*Examples:*
* Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)"/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="16623"/>
</property>
</concept>
</concept>
<concept>
<code value="TE"/>
<display value="therapeutic alternative"/>
<definition
value="**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.
*Examples:*
* ranitidine for Tagamet"/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="16624"/>
</property>
<concept>
<code value="TB"/>
<display value="therapeutic brand"/>
<definition
value="**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics
>
*Examples:*
* Zantac for Tagamet"/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="23105"/>
</property>
</concept>
<concept>
<code value="TG"/>
<display value="therapeutic generic"/>
<definition
value="**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands
>
*Examples:*
* Ranitidine for cimetidine"/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="23106"/>
</property>
</concept>
</concept>
</concept>
<concept>
<code value="F"/>
<display value="formulary"/>
<definition
value="**Description:** This substitution was performed or is permitted based on formulary guidelines."/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="16625"/>
</property>
</concept>
<concept>
<code value="N"/>
<display value="none"/>
<definition value="No substitution occurred or is permitted."/>
<property>
<code value="status"/>
<valueCode value="active"/>
</property>
<property>
<code value="internalId"/>
<valueCode value="16622"/>
</property>
</concept>
</concept>
</CodeSystem>
IG © 2020+ HL7 International - Vocabulary Work Group. Package hl7.terminology#2.1.0 based on FHIR 4.0.1. Generated 2021-03-06
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