HL7 Terminology
2.1.0 - Publication

This page is part of the HL7 Terminology (v2.1.0: Release) based on FHIR R4. This is the current published version in it's permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

: Substance Admin Substitution - JSON Representation

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{
  "resourceType" : "CodeSystem",
  "id" : "v3-substanceAdminSubstitution",
  "language" : "en",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en\" lang=\"en\"><p><b>Properties</b></p><table class=\"grid\"><tr><td><b>Code</b></td><td><b>URL</b></td><td><b>Description</b></td><td><b>Type</b></td></tr><tr><td>Specializes</td><td/><td>The child code is a more narrow version of the concept represented by the parent code.  I.e. Every child concept is also a valid parent concept.  Used to allow determination of subsumption.  Must be transitive, irreflexive, antisymmetric.</td><td>Coding</td></tr><tr><td>Generalizes</td><td/><td>Inverse of Specializes.  Only included as a derived relationship.</td><td>Coding</td></tr><tr><td>internalId</td><td>http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id</td><td>The internal identifier for the concept in the HL7 Access database repository.</td><td>code</td></tr><tr><td>notSelectable</td><td>http://hl7.org/fhir/concept-properties#notSelectable</td><td>Indicates that the code is abstract - only intended to be used as a selector for other concepts</td><td>boolean</td></tr><tr><td>status</td><td>http://hl7.org/fhir/concept-properties#status</td><td>Designation of a concept's state. Normally is not populated unless the state is retired.</td><td>code</td></tr></table><p>This code system http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution defines the following codes:</p><table class=\"codes\"><tr><td><b>Lvl</b></td><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>internalId</b></td><td><b>Not Selectable</b></td><td><b>status</b></td></tr><tr><td>1</td><td style=\"white-space:nowrap\">_ActSubstanceAdminSubstitutionCode<a name=\"v3-substanceAdminSubstitution-_ActSubstanceAdminSubstitutionCode\"> </a></td><td>ActSubstanceAdminSubstitutionCode</td><td>**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.</td><td>21284</td><td>true</td><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">  E<a name=\"v3-substanceAdminSubstitution-E\"> </a></td><td>equivalent</td><td>**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.</td><td>23107</td><td/><td>active</td></tr><tr><td>3</td><td style=\"white-space:nowrap\">    EC<a name=\"v3-substanceAdminSubstitution-EC\"> </a></td><td>equivalent composition</td><td>**Description:** \r\n\r\nSubstitution occurred or is permitted with another product that is a:\r\n\r\n *  pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n *  pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n *  *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n *  *Pharmaceutical equivalent:* Lisonpril for Zestril</td><td>23108</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      BC<a name=\"v3-substanceAdminSubstitution-BC\"> </a></td><td>brand composition</td><td>**Description:** \r\n\r\nSubstitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n *  Zestril for Prinivil\r\n *  Coumadin for Jantoven</td><td>23109</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      G<a name=\"v3-substanceAdminSubstitution-G\"> </a></td><td>generic composition</td><td>**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n *  Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)</td><td>16623</td><td/><td>active</td></tr><tr><td>3</td><td style=\"white-space:nowrap\">    TE<a name=\"v3-substanceAdminSubstitution-TE\"> </a></td><td>therapeutic alternative</td><td>**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n *  ranitidine for Tagamet</td><td>16624</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      TB<a name=\"v3-substanceAdminSubstitution-TB\"> </a></td><td>therapeutic brand</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n&gt;\r\n\r\n*Examples:* \r\n\r\n *  Zantac for Tagamet</td><td>23105</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      TG<a name=\"v3-substanceAdminSubstitution-TG\"> </a></td><td>therapeutic generic</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n&gt;\r\n\r\n*Examples:* \r\n\r\n *  Ranitidine for cimetidine</td><td>23106</td><td/><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">  F<a name=\"v3-substanceAdminSubstitution-F\"> </a></td><td>formulary</td><td>**Description:** This substitution was performed or is permitted based on formulary guidelines.</td><td>16625</td><td/><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">  N<a name=\"v3-substanceAdminSubstitution-N\"> </a></td><td>none</td><td>No substitution occurred or is permitted.</td><td>16622</td><td/><td>active</td></tr></table></div>"
  },
  "url" : "http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution",
  "identifier" : [
    {
      "system" : "urn:ietf:rfc:3986",
      "value" : "urn:oid:2.16.840.1.113883.5.1070"
    }
  ],
  "version" : "2.0.0",
  "name" : "SubstanceAdminSubstitution",
  "title" : "Substance Admin Substitution",
  "status" : "active",
  "date" : "2019-03-20",
  "publisher" : "Health Level 7",
  "contact" : [
    {
      "name" : "Health Level Seven"
    }
  ],
  "description" : "Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.",
  "hierarchyMeaning" : "is-a",
  "content" : "complete",
  "property" : [
    {
      "extension" : [
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry",
          "valueCode" : "antisymmetric"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity",
          "valueCode" : "transitive"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity",
          "valueCode" : "irreflexive"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable",
          "valueBoolean" : true
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind",
          "valueCode" : "Specializes"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName",
          "valueString" : "Generalizes"
        }
      ],
      "code" : "Specializes",
      "description" : "The child code is a more narrow version of the concept represented by the parent code.  I.e. Every child concept is also a valid parent concept.  Used to allow determination of subsumption.  Must be transitive, irreflexive, antisymmetric.",
      "type" : "Coding"
    },
    {
      "extension" : [
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry",
          "valueCode" : "antisymmetric"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity",
          "valueCode" : "transitive"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity",
          "valueCode" : "irreflexive"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable",
          "valueBoolean" : true
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind",
          "valueCode" : "Generalizes"
        },
        {
          "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName",
          "valueString" : "Specializes"
        }
      ],
      "code" : "Generalizes",
      "description" : "Inverse of Specializes.  Only included as a derived relationship.",
      "type" : "Coding"
    },
    {
      "code" : "internalId",
      "uri" : "http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id",
      "description" : "The internal identifier for the concept in the HL7 Access database repository.",
      "type" : "code"
    },
    {
      "code" : "notSelectable",
      "uri" : "http://hl7.org/fhir/concept-properties#notSelectable",
      "description" : "Indicates that the code is abstract - only intended to be used as a selector for other concepts",
      "type" : "boolean"
    },
    {
      "code" : "status",
      "uri" : "http://hl7.org/fhir/concept-properties#status",
      "description" : "Designation of a concept's state. Normally is not populated unless the state is retired.",
      "type" : "code"
    }
  ],
  "concept" : [
    {
      "code" : "_ActSubstanceAdminSubstitutionCode",
      "display" : "ActSubstanceAdminSubstitutionCode",
      "definition" : "**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.",
      "property" : [
        {
          "code" : "notSelectable",
          "valueBoolean" : true
        },
        {
          "code" : "status",
          "valueCode" : "active"
        },
        {
          "code" : "internalId",
          "valueCode" : "21284"
        }
      ],
      "concept" : [
        {
          "code" : "E",
          "display" : "equivalent",
          "definition" : "**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.",
          "property" : [
            {
              "code" : "status",
              "valueCode" : "active"
            },
            {
              "code" : "internalId",
              "valueCode" : "23107"
            }
          ],
          "concept" : [
            {
              "code" : "EC",
              "display" : "equivalent composition",
              "definition" : "**Description:** \r\n\r\nSubstitution occurred or is permitted with another product that is a:\r\n\r\n *  pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n *  pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n *  *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n *  *Pharmaceutical equivalent:* Lisonpril for Zestril",
              "property" : [
                {
                  "code" : "status",
                  "valueCode" : "active"
                },
                {
                  "code" : "internalId",
                  "valueCode" : "23108"
                }
              ],
              "concept" : [
                {
                  "code" : "BC",
                  "display" : "brand composition",
                  "definition" : "**Description:** \r\n\r\nSubstitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n *  Zestril for Prinivil\r\n *  Coumadin for Jantoven",
                  "property" : [
                    {
                      "code" : "status",
                      "valueCode" : "active"
                    },
                    {
                      "code" : "internalId",
                      "valueCode" : "23109"
                    }
                  ]
                },
                {
                  "code" : "G",
                  "display" : "generic composition",
                  "definition" : "**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n *  Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)",
                  "property" : [
                    {
                      "code" : "status",
                      "valueCode" : "active"
                    },
                    {
                      "code" : "internalId",
                      "valueCode" : "16623"
                    }
                  ]
                }
              ]
            },
            {
              "code" : "TE",
              "display" : "therapeutic alternative",
              "definition" : "**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n *  ranitidine for Tagamet",
              "property" : [
                {
                  "code" : "status",
                  "valueCode" : "active"
                },
                {
                  "code" : "internalId",
                  "valueCode" : "16624"
                }
              ],
              "concept" : [
                {
                  "code" : "TB",
                  "display" : "therapeutic brand",
                  "definition" : "**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n *  Zantac for Tagamet",
                  "property" : [
                    {
                      "code" : "status",
                      "valueCode" : "active"
                    },
                    {
                      "code" : "internalId",
                      "valueCode" : "23105"
                    }
                  ]
                },
                {
                  "code" : "TG",
                  "display" : "therapeutic generic",
                  "definition" : "**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n *  Ranitidine for cimetidine",
                  "property" : [
                    {
                      "code" : "status",
                      "valueCode" : "active"
                    },
                    {
                      "code" : "internalId",
                      "valueCode" : "23106"
                    }
                  ]
                }
              ]
            }
          ]
        },
        {
          "code" : "F",
          "display" : "formulary",
          "definition" : "**Description:** This substitution was performed or is permitted based on formulary guidelines.",
          "property" : [
            {
              "code" : "status",
              "valueCode" : "active"
            },
            {
              "code" : "internalId",
              "valueCode" : "16625"
            }
          ]
        },
        {
          "code" : "N",
          "display" : "none",
          "definition" : "No substitution occurred or is permitted.",
          "property" : [
            {
              "code" : "status",
              "valueCode" : "active"
            },
            {
              "code" : "internalId",
              "valueCode" : "16622"
            }
          ]
        }
      ]
    }
  ]
}