HL7 Terminology
2.1.0 - Publication

This page is part of the HL7 Terminology (v2.1.0: Release) based on FHIR R4. This is the current published version in it's permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

: Substance Admin Substitution - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:CodeSystem;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "v3-substanceAdminSubstitution"];
  fhir:Resource.language [ fhir:value "en"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en\" lang=\"en\"><p><b>Properties</b></p><table class=\"grid\"><tr><td><b>Code</b></td><td><b>URL</b></td><td><b>Description</b></td><td><b>Type</b></td></tr><tr><td>Specializes</td><td/><td>The child code is a more narrow version of the concept represented by the parent code.  I.e. Every child concept is also a valid parent concept.  Used to allow determination of subsumption.  Must be transitive, irreflexive, antisymmetric.</td><td>Coding</td></tr><tr><td>Generalizes</td><td/><td>Inverse of Specializes.  Only included as a derived relationship.</td><td>Coding</td></tr><tr><td>internalId</td><td>http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id</td><td>The internal identifier for the concept in the HL7 Access database repository.</td><td>code</td></tr><tr><td>notSelectable</td><td>http://hl7.org/fhir/concept-properties#notSelectable</td><td>Indicates that the code is abstract - only intended to be used as a selector for other concepts</td><td>boolean</td></tr><tr><td>status</td><td>http://hl7.org/fhir/concept-properties#status</td><td>Designation of a concept's state. Normally is not populated unless the state is retired.</td><td>code</td></tr></table><p>This code system http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution defines the following codes:</p><table class=\"codes\"><tr><td><b>Lvl</b></td><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>internalId</b></td><td><b>Not Selectable</b></td><td><b>status</b></td></tr><tr><td>1</td><td style=\"white-space:nowrap\">_ActSubstanceAdminSubstitutionCode<a name=\"v3-substanceAdminSubstitution-_ActSubstanceAdminSubstitutionCode\"> </a></td><td>ActSubstanceAdminSubstitutionCode</td><td>**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.</td><td>21284</td><td>true</td><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">  E<a name=\"v3-substanceAdminSubstitution-E\"> </a></td><td>equivalent</td><td>**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.</td><td>23107</td><td/><td>active</td></tr><tr><td>3</td><td style=\"white-space:nowrap\">    EC<a name=\"v3-substanceAdminSubstitution-EC\"> </a></td><td>equivalent composition</td><td>**Description:** \r\n\r\nSubstitution occurred or is permitted with another product that is a:\r\n\r\n *  pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n *  pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n *  *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n *  *Pharmaceutical equivalent:* Lisonpril for Zestril</td><td>23108</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      BC<a name=\"v3-substanceAdminSubstitution-BC\"> </a></td><td>brand composition</td><td>**Description:** \r\n\r\nSubstitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n *  Zestril for Prinivil\r\n *  Coumadin for Jantoven</td><td>23109</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      G<a name=\"v3-substanceAdminSubstitution-G\"> </a></td><td>generic composition</td><td>**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n *  Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)</td><td>16623</td><td/><td>active</td></tr><tr><td>3</td><td style=\"white-space:nowrap\">    TE<a name=\"v3-substanceAdminSubstitution-TE\"> </a></td><td>therapeutic alternative</td><td>**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n *  ranitidine for Tagamet</td><td>16624</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      TB<a name=\"v3-substanceAdminSubstitution-TB\"> </a></td><td>therapeutic brand</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n&gt;\r\n\r\n*Examples:* \r\n\r\n *  Zantac for Tagamet</td><td>23105</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">      TG<a name=\"v3-substanceAdminSubstitution-TG\"> </a></td><td>therapeutic generic</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n&gt;\r\n\r\n*Examples:* \r\n\r\n *  Ranitidine for cimetidine</td><td>23106</td><td/><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">  F<a name=\"v3-substanceAdminSubstitution-F\"> </a></td><td>formulary</td><td>**Description:** This substitution was performed or is permitted based on formulary guidelines.</td><td>16625</td><td/><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">  N<a name=\"v3-substanceAdminSubstitution-N\"> </a></td><td>none</td><td>No substitution occurred or is permitted.</td><td>16622</td><td/><td>active</td></tr></table></div>"
  ];
  fhir:CodeSystem.url [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution"];
  fhir:CodeSystem.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "urn:ietf:rfc:3986" ];
     fhir:Identifier.value [ fhir:value "urn:oid:2.16.840.1.113883.5.1070" ]
  ];
  fhir:CodeSystem.version [ fhir:value "2.0.0"];
  fhir:CodeSystem.name [ fhir:value "SubstanceAdminSubstitution"];
  fhir:CodeSystem.title [ fhir:value "Substance Admin Substitution"];
  fhir:CodeSystem.status [ fhir:value "active"];
  fhir:CodeSystem.date [ fhir:value "2019-03-20"^^xsd:date];
  fhir:CodeSystem.publisher [ fhir:value "Health Level 7"];
  fhir:CodeSystem.contact [
     fhir:index 0;
     fhir:ContactDetail.name [ fhir:value "Health Level Seven" ]
  ];
  fhir:CodeSystem.description [ fhir:value "Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided."];
  fhir:CodeSystem.hierarchyMeaning [ fhir:value "is-a"];
  fhir:CodeSystem.content [ fhir:value "complete"];
  fhir:CodeSystem.property [
     fhir:index 0;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry" ];
       fhir:Extension.valueCode [ fhir:value "antisymmetric" ]     ], [
       fhir:index 1;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity" ];
       fhir:Extension.valueCode [ fhir:value "transitive" ]     ], [
       fhir:index 2;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity" ];
       fhir:Extension.valueCode [ fhir:value "irreflexive" ]     ], [
       fhir:index 3;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable" ];
       fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]     ], [
       fhir:index 4;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind" ];
       fhir:Extension.valueCode [ fhir:value "Specializes" ]     ], [
       fhir:index 5;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName" ];
       fhir:Extension.valueString [ fhir:value "Generalizes" ]     ];
     fhir:CodeSystem.property.code [ fhir:value "Specializes" ];
     fhir:CodeSystem.property.description [ fhir:value "The child code is a more narrow version of the concept represented by the parent code.  I.e. Every child concept is also a valid parent concept.  Used to allow determination of subsumption.  Must be transitive, irreflexive, antisymmetric." ];
     fhir:CodeSystem.property.type [ fhir:value "Coding" ]
  ], [
     fhir:index 1;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry" ];
       fhir:Extension.valueCode [ fhir:value "antisymmetric" ]     ], [
       fhir:index 1;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity" ];
       fhir:Extension.valueCode [ fhir:value "transitive" ]     ], [
       fhir:index 2;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity" ];
       fhir:Extension.valueCode [ fhir:value "irreflexive" ]     ], [
       fhir:index 3;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable" ];
       fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]     ], [
       fhir:index 4;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind" ];
       fhir:Extension.valueCode [ fhir:value "Generalizes" ]     ], [
       fhir:index 5;
       fhir:Extension.url [ fhir:value "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName" ];
       fhir:Extension.valueString [ fhir:value "Specializes" ]     ];
     fhir:CodeSystem.property.code [ fhir:value "Generalizes" ];
     fhir:CodeSystem.property.description [ fhir:value "Inverse of Specializes.  Only included as a derived relationship." ];
     fhir:CodeSystem.property.type [ fhir:value "Coding" ]
  ], [
     fhir:index 2;
     fhir:CodeSystem.property.code [ fhir:value "internalId" ];
     fhir:CodeSystem.property.uri [ fhir:value "http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id" ];
     fhir:CodeSystem.property.description [ fhir:value "The internal identifier for the concept in the HL7 Access database repository." ];
     fhir:CodeSystem.property.type [ fhir:value "code" ]
  ], [
     fhir:index 3;
     fhir:CodeSystem.property.code [ fhir:value "notSelectable" ];
     fhir:CodeSystem.property.uri [ fhir:value "http://hl7.org/fhir/concept-properties#notSelectable" ];
     fhir:CodeSystem.property.description [ fhir:value "Indicates that the code is abstract - only intended to be used as a selector for other concepts" ];
     fhir:CodeSystem.property.type [ fhir:value "boolean" ]
  ], [
     fhir:index 4;
     fhir:CodeSystem.property.code [ fhir:value "status" ];
     fhir:CodeSystem.property.uri [ fhir:value "http://hl7.org/fhir/concept-properties#status" ];
     fhir:CodeSystem.property.description [ fhir:value "Designation of a concept's state. Normally is not populated unless the state is retired." ];
     fhir:CodeSystem.property.type [ fhir:value "code" ]
  ];
  fhir:CodeSystem.concept [
     fhir:index 0;
     fhir:CodeSystem.concept.code [ fhir:value "_ActSubstanceAdminSubstitutionCode" ];
     fhir:CodeSystem.concept.display [ fhir:value "ActSubstanceAdminSubstitutionCode" ];
     fhir:CodeSystem.concept.definition [ fhir:value "**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects." ];
     fhir:CodeSystem.concept.property [
       fhir:index 0;
       fhir:CodeSystem.concept.property.code [ fhir:value "notSelectable" ];
       fhir:CodeSystem.concept.property.valueBoolean [ fhir:value "true"^^xsd:boolean ]     ], [
       fhir:index 1;
       fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
       fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]     ], [
       fhir:index 2;
       fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
       fhir:CodeSystem.concept.property.valueCode [ fhir:value "21284" ]     ];
     fhir:CodeSystem.concept.concept [
       fhir:index 0;
       fhir:CodeSystem.concept.code [ fhir:value "E" ];
       fhir:CodeSystem.concept.display [ fhir:value "equivalent" ];
       fhir:CodeSystem.concept.definition [ fhir:value "**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product." ];
       fhir:CodeSystem.concept.property [
         fhir:index 0;
         fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
         fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]       ], [
         fhir:index 1;
         fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
         fhir:CodeSystem.concept.property.valueCode [ fhir:value "23107" ]       ];
       fhir:CodeSystem.concept.concept [
         fhir:index 0;
         fhir:CodeSystem.concept.code [ fhir:value "EC" ];
         fhir:CodeSystem.concept.display [ fhir:value "equivalent composition" ];
         fhir:CodeSystem.concept.definition [ fhir:value "**Description:** \r\n\r\nSubstitution occurred or is permitted with another product that is a:\r\n\r\n *  pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n *  pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n *  *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n *  *Pharmaceutical equivalent:* Lisonpril for Zestril" ];
         fhir:CodeSystem.concept.property [
           fhir:index 0;
           fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
           fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]         ], [
           fhir:index 1;
           fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
           fhir:CodeSystem.concept.property.valueCode [ fhir:value "23108" ]         ];
         fhir:CodeSystem.concept.concept [
           fhir:index 0;
           fhir:CodeSystem.concept.code [ fhir:value "BC" ];
           fhir:CodeSystem.concept.display [ fhir:value "brand composition" ];
           fhir:CodeSystem.concept.definition [ fhir:value "**Description:** \r\n\r\nSubstitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n *  Zestril for Prinivil\r\n *  Coumadin for Jantoven" ];
           fhir:CodeSystem.concept.property [
             fhir:index 0;
             fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]           ], [
             fhir:index 1;
             fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "23109" ]           ]         ], [
           fhir:index 1;
           fhir:CodeSystem.concept.code [ fhir:value "G" ];
           fhir:CodeSystem.concept.display [ fhir:value "generic composition" ];
           fhir:CodeSystem.concept.definition [ fhir:value "**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n *  Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)" ];
           fhir:CodeSystem.concept.property [
             fhir:index 0;
             fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]           ], [
             fhir:index 1;
             fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "16623" ]           ]         ]       ], [
         fhir:index 1;
         fhir:CodeSystem.concept.code [ fhir:value "TE" ];
         fhir:CodeSystem.concept.display [ fhir:value "therapeutic alternative" ];
         fhir:CodeSystem.concept.definition [ fhir:value "**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n *  ranitidine for Tagamet" ];
         fhir:CodeSystem.concept.property [
           fhir:index 0;
           fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
           fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]         ], [
           fhir:index 1;
           fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
           fhir:CodeSystem.concept.property.valueCode [ fhir:value "16624" ]         ];
         fhir:CodeSystem.concept.concept [
           fhir:index 0;
           fhir:CodeSystem.concept.code [ fhir:value "TB" ];
           fhir:CodeSystem.concept.display [ fhir:value "therapeutic brand" ];
           fhir:CodeSystem.concept.definition [ fhir:value "**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n *  Zantac for Tagamet" ];
           fhir:CodeSystem.concept.property [
             fhir:index 0;
             fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]           ], [
             fhir:index 1;
             fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "23105" ]           ]         ], [
           fhir:index 1;
           fhir:CodeSystem.concept.code [ fhir:value "TG" ];
           fhir:CodeSystem.concept.display [ fhir:value "therapeutic generic" ];
           fhir:CodeSystem.concept.definition [ fhir:value "**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n *  Ranitidine for cimetidine" ];
           fhir:CodeSystem.concept.property [
             fhir:index 0;
             fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]           ], [
             fhir:index 1;
             fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
             fhir:CodeSystem.concept.property.valueCode [ fhir:value "23106" ]           ]         ]       ]     ], [
       fhir:index 1;
       fhir:CodeSystem.concept.code [ fhir:value "F" ];
       fhir:CodeSystem.concept.display [ fhir:value "formulary" ];
       fhir:CodeSystem.concept.definition [ fhir:value "**Description:** This substitution was performed or is permitted based on formulary guidelines." ];
       fhir:CodeSystem.concept.property [
         fhir:index 0;
         fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
         fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]       ], [
         fhir:index 1;
         fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
         fhir:CodeSystem.concept.property.valueCode [ fhir:value "16625" ]       ]     ], [
       fhir:index 2;
       fhir:CodeSystem.concept.code [ fhir:value "N" ];
       fhir:CodeSystem.concept.display [ fhir:value "none" ];
       fhir:CodeSystem.concept.definition [ fhir:value "No substitution occurred or is permitted." ];
       fhir:CodeSystem.concept.property [
         fhir:index 0;
         fhir:CodeSystem.concept.property.code [ fhir:value "status" ];
         fhir:CodeSystem.concept.property.valueCode [ fhir:value "active" ]       ], [
         fhir:index 1;
         fhir:CodeSystem.concept.property.code [ fhir:value "internalId" ];
         fhir:CodeSystem.concept.property.valueCode [ fhir:value "16622" ]       ]     ]
  ].

# - ontology header ------------------------------------------------------------

 a owl:Ontology;
  owl:imports fhir:fhir.ttl.