HL7 Terminology (THO)
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This page is part of the HL7 Terminology (v5.5.0: Release) based on FHIR (HL7® FHIR® Standard) R4. This is the current published version. For a full list of available versions, see the Directory of published versions

ValueSet: RoleClassIngredientEntity

Official URL: http://terminology.hl7.org/ValueSet/v3-RoleClassIngredientEntity Version: 3.0.0
Active as of 2014-03-26 Responsible: Health Level Seven International Computable Name: RoleClassIngredientEntity
Other Identifiers: urn:ietf:rfc:3986#Uniform Resource Identifier (URI)#urn:oid:2.16.840.1.113883.1.11.10430

Copyright/Legal: This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license

Relates a component (player) to a mixture (scoper). E.g., Glucose and Water are ingredients of D5W, latex may be an ingredient in a tracheal tube.

References

This value set is not used here; it may be used elsewhere (e.g. specifications and/or implementations that use this content)

Logical Definition (CLD)

 

Expansion

Expansion based on codesystem RoleClass v4.0.0 (CodeSystem)

This value set contains 15 concepts.

LevelCodeSystemDisplayDefinition
1  INGRhttp://terminology.hl7.org/CodeSystem/v3-RoleClassingredient

Relates a component (player) to a mixture (scoper). E.g., Glucose and Water are ingredients of D5W, latex may be an ingredient in a tracheal tube.

2    ACTIhttp://terminology.hl7.org/CodeSystem/v3-RoleClassactive ingredient

Definition: a therapeutically active ingredient (player) in a mixture (scoper), where the mixture is typically a manufactured pharmaceutical. It is unknown if the quantity of such an ingredient is expressed precisely in terms of the playing ingredient substance, or, if it is specified in terms of a closely related substance (active moiety or reference substance).

3      ACTIBhttp://terminology.hl7.org/CodeSystem/v3-RoleClassactive ingredient - basis of strength

Description: Active ingredient, where the ingredient substance (player) is itself the "basis of strength", i.e., where the Role.quantity specifies exactly the quantity of the player substance in the medicine formulation.

Examples: Lopressor 50 mg actually contains 50 mg of metoprolol succinate, even though the active moiety is metoprolol, but also: Tenormin 50 mg contain 50 mg of atenolol, as free base, i.e., where the active ingredient atenolol is also the active moiety.

3      ACTIMhttp://terminology.hl7.org/CodeSystem/v3-RoleClassactive ingredient - moiety is basis of strength

Description: Active ingredient, where not the ingredient substance (player), but itaTMs active moiety is the "basis of strength", i.e., where the Role.quantity specifies the quantity of the player substance's active moiety in the medicine formulation.

Examples: 1 mL of Betopic 5mg/mL eye drops contains 5.6 mg betaxolol hydrochloride equivalent to betaxolol base 5 mg.

3      ACTIRhttp://terminology.hl7.org/CodeSystem/v3-RoleClassactive ingredient - reference substance is basis of strength

Description: Active ingredient, where not the ingredient substance (player) but another reference substance with the same active moiety, is the "basis of strength", i.e., where the Role.quantity specifies the quantity of a reference substance, similar but different from the player substance's in the medicine formulation.

Examples: Toprol-XL 50 mg contains 47.5 mg of metoprolol succinate equivalent to 50 mg of metoprolol tartrate.

2    ADJVhttp://terminology.hl7.org/CodeSystem/v3-RoleClassadjuvant

A component (player) added to enhance the action of an active ingredient (scoper) (in the manner of a catalyst) but which has no active effect in and of itself. Such ingredients are significant in defining equivalence of products in a way that inactive ingredients are not.

2    ADTVhttp://terminology.hl7.org/CodeSystem/v3-RoleClassadditive

An ingredient (player) that is added to a base (scoper), that amounts to a minor part of the overall mixture.

2    BASEhttp://terminology.hl7.org/CodeSystem/v3-RoleClassbase

A base ingredient (player) is what comprises the major part of a mixture (scoper). E.g., Water in most i.v. solutions, or Vaseline in salves. Among all ingredients of a material, there should be only one base. A base substance can, in turn, be a mixture.

2    CNTMhttp://terminology.hl7.org/CodeSystem/v3-RoleClasscontaminant ingredient

An ingredient whose presence is not intended but may not be reasonably avoided given the circumstances of the mixture's nature or origin.

2    IACThttp://terminology.hl7.org/CodeSystem/v3-RoleClassinactive ingredient

An ingredient which is not considered therapeutically active, e.g., colors, flavors, stabilizers, or preservatives, fillers, or structural components added to an active ingredient in order to facilitate administration of the active ingredient but without being considered therapeutically active. An inactive ingredient need not be biologically inert, e.g., might be active as an allergen or might have a pleasant taste, but is not an essential constituent delivering the therapeutic effect.

3      COLRhttp://terminology.hl7.org/CodeSystem/v3-RoleClasscolor additive

A substance (player) influencing the optical aspect of material (scoper).

3      FLVRhttp://terminology.hl7.org/CodeSystem/v3-RoleClassflavor additive

A substance (player) added to a mixture (scoper) to make it taste a certain way. In food the use is obvious, in pharmaceuticals flavors can hide disgusting taste of the active ingredient (important in pediatric treatments).

3      PRSVhttp://terminology.hl7.org/CodeSystem/v3-RoleClasspreservative

A substance (player) added to a mixture (scoper) to prevent microorganisms (fungi, bacteria) to spoil the mixture.

3      STBLhttp://terminology.hl7.org/CodeSystem/v3-RoleClassstabilizer

A stabilizer (player) added to a mixture (scoper) in order to prevent the molecular disintegration of the main substance.

2    MECHhttp://terminology.hl7.org/CodeSystem/v3-RoleClassmechanical ingredient

An ingredient (player) of a medication (scoper) that is inseparable from the active ingredients, but has no intended chemical or pharmaceutical effect itself, but which may have some systemic effect on the patient.

An example is a collagen matrix used as a base for transplanting skin cells. The collagen matrix can be left permanently in the graft site. Because it is of bovine origin, the patient may exhibit allergies or may have cultural objections to its use.


Explanation of the columns that may appear on this page:

Level A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code The code (used as the code in the resource instance)
Display The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition An explanation of the meaning of the concept
Comments Additional notes about how to use the code

History

DateActionAuthorCustodianComment
2023-11-14reviseMarc DuteauTSMGAdd standard copyright and contact to internal content; up-476
2022-10-18reviseMarc DuteauTSMGFixing missing metadata; up-349
2020-05-06reviseTed KleinVocabulary WGMigrated to the UTG maintenance environment and publishing tooling.
2014-03-26reviseVocabulary (Woody Beeler) (no record of original request)2014T1_2014-03-26_001283 (RIM release ID)Lock all vaue sets untouched since 2014-03-26 to trackingId 2014T1_2014_03_26