HL7 Terminology (THO)
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This page is part of the HL7 Terminology (v5.4.0: Release) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions

CodeSystem: Substance Admin Substitution

Official URL: http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution Version: 3.0.0
Active as of 2019-03-20 Responsible: Health Level Seven International Computable Name: SubstanceAdminSubstitution
Other Identifiers: id: Uniform Resource Identifier (URI)#urn:oid:2.16.840.1.113883.5.1070

Copyright/Legal: This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license

Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.

This Code system is referenced in the content logical definition of the following value sets:

Properties

This code system defines the following properties for its concepts

CodeURITypeDescription
SpecializesCodingThe child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.
GeneralizesCodingInverse of Specializes. Only included as a derived relationship.
internalIdhttp://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-idcodeThe internal identifier for the concept in the HL7 Access database repository.
notSelectablehttp://hl7.org/fhir/concept-properties#notSelectablebooleanIndicates that the code is abstract - only intended to be used as a selector for other concepts
statushttp://hl7.org/fhir/concept-properties#statuscodeDesignation of a concept's state. Normally is not populated unless the state is retired.

Concepts

This case-sensitive code system http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution defines the following codes in a Is-A heirarchy:

LvlCodeDisplayDefinitioninternalIdNot Selectablestatus
1_ActSubstanceAdminSubstitutionCode ActSubstanceAdminSubstitutionCode

Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.

21284trueactive
2  E equivalent

Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.

23107active
3    EC equivalent composition

Description:

Substitution occurred or is permitted with another product that is a:

  • pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
  • pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration

Examples:

  • Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate
  • Pharmaceutical equivalent: Lisonpril for Zestril
23108active
4      BC brand composition

Description:

Substitution occurred or is permitted between equivalent Brands but not Generics

Examples:

  • Zestril for Prinivil
  • Coumadin for Jantoven
23109active
4      G generic composition

Description: Substitution occurred or is permitted between equivalent Generics but not Brands

Examples:

  • Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)
16623active
3    TE therapeutic alternative

Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.

Examples:

  • ranitidine for Tagamet
16624active
4      TB therapeutic brand

Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics

Examples:

  • Zantac for Tagamet
23105active
4      TG therapeutic generic

Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands

Examples:

  • Ranitidine for cimetidine
23106active
2  F formulary

Description: This substitution was performed or is permitted based on formulary guidelines.

16625active
2  N none

No substitution occurred or is permitted.

16622active

History

DateActionAuthorCustodianComment
2023-11-14reviseMarc DuteauTSMGAdd standard copyright and contact to internal content; up-476
2022-10-18reviseMarc DuteauTSMGFixing missing metadata; up-349
2022-02-17 00:00:32+1100reviseGrahame GrieveVocabulary WGPopulate Missing caseSensitive property; UP-286
2020-05-06reviseTed KleinVocabulary WGMigrated to the UTG maintenance environment and publishing tooling.