HL7 Terminology (THO)
6.1.0 - Publication International flag

This page is part of the HL7 Terminology (v6.1.0: Release) based on FHIR (HL7® FHIR® Standard) v5.0.0. This is the current published version. For a full list of available versions, see the Directory of published versions

CodeSystem: Substance Admin Substitution

Official URL: http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution Version: 3.0.0
Active as of 2019-03-20 Responsible: Health Level Seven International Computable Name: SubstanceAdminSubstitution
Other Identifiers: OID:2.16.840.1.113883.5.1070

Copyright/Legal: This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html

Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.

This Code system is referenced in the content logical definition of the following value sets:

Generated Narrative: CodeSystem v3-substanceAdminSubstitution

Language: en

Properties

This code system defines the following properties for its concepts

NameCodeURITypeDescription
Specializes Specializes Coding The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.
Generalizes Generalizes Coding Inverse of Specializes. Only included as a derived relationship.
internalId internalId http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id code The internal identifier for the concept in the HL7 Access database repository.
Not Selectable notSelectable http://hl7.org/fhir/concept-properties#notSelectable boolean Indicates that the code is abstract - only intended to be used as a selector for other concepts
Status status http://hl7.org/fhir/concept-properties#status code Designation of a concept's state. Normally is not populated unless the state is retired.

Concepts

This case-sensitive code system http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution defines the following codes in a Is-A hierarchy:

LvlCodeDisplayDefinitioninternalIdNot SelectableStatus
1 _ActSubstanceAdminSubstitutionCode ActSubstanceAdminSubstitutionCode

Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.

21284 true active
2   E equivalent

Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.

23107 active
3     EC equivalent composition

Substitution occurred or is permitted with another product that is a:

  • pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
  • pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration

Examples:

  • Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate
  • Pharmaceutical equivalent: Lisonpril for Zestril
23108 active
4       BC brand composition

Substitution occurred or is permitted between equivalent Brands but not Generics

Examples:

  • Zestril for Prinivil
  • Coumadin for Jantoven
23109 active
4       G generic composition

Substitution occurred or is permitted between equivalent Generics but not Brands

Examples:

  • Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)
16623 active
3     TE therapeutic alternative

Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.

Examples:

  • ranitidine for Tagamet
16624 active
4       TB therapeutic brand

Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics

Examples:

  • Zantac for Tagamet
23105 active
4       TG therapeutic generic

Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands

Examples:

  • Ranitidine for cimetidine
23106 active
2   F formulary

This substitution was performed or is permitted based on formulary guidelines.

16625 active
2   N none

No substitution occurred or is permitted.

16622 active

History

DateActionCustodianAuthorComment
2024-07-12revisePharmacyRosemary HofstedeallowedCodeableConcept codes have **Definition** in front of the definitions and shouldn't; up-556
2023-11-14reviseTSMGMarc DuteauAdd standard copyright and contact to internal content; up-476
2022-10-18reviseTSMGMarc DuteauFixing missing metadata; up-349
2022-02-17 00:00:32+1100reviseVocabulary WGGrahame GrievePopulate Missing caseSensitive property; UP-286
2020-05-06reviseVocabulary WGTed KleinMigrated to the UTG maintenance environment and publishing tooling.