| Lvl | Code | Display | Definition | Not Selectable | Status |
| 1 | _ActSubstanceAdminSubstitutionCode | ActSubstanceAdminSubstitutionCode | Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects. \n | true | active |
| 2 | E | equivalent | Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product. \n | | active |
| 3 | EC | equivalent composition | Substitution occurred or is permitted with another product that is a: \n \n- pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
\n- pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration
\n \n Examples: \n \n- Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate
\n- Pharmaceutical equivalent: Lisonpril for Zestril
\n \n | | active |
| 4 | BC | brand composition | Substitution occurred or is permitted between equivalent Brands but not Generics \n Examples: \n \n- Zestril for Prinivil
\n- Coumadin for Jantoven
\n \n | | active |
| 4 | G | generic composition | Substitution occurred or is permitted between equivalent Generics but not Brands \n Examples: \n \n- Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)
\n \n | | active |
| 3 | TE | therapeutic alternative | Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile. \n Examples: \n \n- ranitidine for Tagamet
\n \n | | active |
| 4 | TB | therapeutic brand | Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics \n \n \n Examples: \n \n | | active |
| 4 | TG | therapeutic generic | Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands \n \n \n Examples: \n \n- Ranitidine for cimetidine
\n \n | | active |
| 2 | F | formulary | This substitution was performed or is permitted based on formulary guidelines. \n | | active |
| 2 | N | none | No substitution occurred or is permitted. \n | | active |