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{ "resourceType" : "CodeSystem", "id" : "v3-substanceAdminSubstitution", "language" : "en", "text" : { "status" : "generated", "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en\" lang=\"en\"><h2>Substance Admin Substitution</h2><div><p>Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.</p>\n</div><p><b>Properties</b></p><table class=\"grid\"><tr><td><b>Code</b></td><td><b>URL</b></td><td><b>Description</b></td><td><b>Type</b></td></tr><tr><td>Specializes</td><td/><td>The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.</td><td>Coding</td></tr><tr><td>Generalizes</td><td/><td>Inverse of Specializes. Only included as a derived relationship.</td><td>Coding</td></tr><tr><td>internalId</td><td>http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id</td><td>The internal identifier for the concept in the HL7 Access database repository.</td><td>code</td></tr><tr><td>notSelectable</td><td>http://hl7.org/fhir/concept-properties#notSelectable</td><td>Indicates that the code is abstract - only intended to be used as a selector for other concepts</td><td>boolean</td></tr><tr><td>status</td><td>http://hl7.org/fhir/concept-properties#status</td><td>Designation of a concept's state. Normally is not populated unless the state is retired.</td><td>code</td></tr></table><p>This code system http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution defines the following codes:</p><table class=\"codes\"><tr><td><b>Lvl</b></td><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>internalId</b></td><td><b>Not Selectable</b></td><td><b>status</b></td></tr><tr><td>1</td><td style=\"white-space:nowrap\">_ActSubstanceAdminSubstitutionCode<a name=\"v3-substanceAdminSubstitution-_ActSubstanceAdminSubstitutionCode\"> </a></td><td>ActSubstanceAdminSubstitutionCode</td><td>**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.</td><td>21284</td><td>true</td><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\"> E<a name=\"v3-substanceAdminSubstitution-E\"> </a></td><td>equivalent</td><td>**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.</td><td>23107</td><td/><td>active</td></tr><tr><td>3</td><td style=\"white-space:nowrap\"> EC<a name=\"v3-substanceAdminSubstitution-EC\"> </a></td><td>equivalent composition</td><td>**Description:** \r\n\r\nSubstitution occurred or is permitted with another product that is a:\r\n\r\n * pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n * pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n * *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n * *Pharmaceutical equivalent:* Lisonpril for Zestril</td><td>23108</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\"> BC<a name=\"v3-substanceAdminSubstitution-BC\"> </a></td><td>brand composition</td><td>**Description:** \r\n\r\nSubstitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n * Zestril for Prinivil\r\n * Coumadin for Jantoven</td><td>23109</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\"> G<a name=\"v3-substanceAdminSubstitution-G\"> </a></td><td>generic composition</td><td>**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n * Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)</td><td>16623</td><td/><td>active</td></tr><tr><td>3</td><td style=\"white-space:nowrap\"> TE<a name=\"v3-substanceAdminSubstitution-TE\"> </a></td><td>therapeutic alternative</td><td>**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n * ranitidine for Tagamet</td><td>16624</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\"> TB<a name=\"v3-substanceAdminSubstitution-TB\"> </a></td><td>therapeutic brand</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n * Zantac for Tagamet</td><td>23105</td><td/><td>active</td></tr><tr><td>4</td><td style=\"white-space:nowrap\"> TG<a name=\"v3-substanceAdminSubstitution-TG\"> </a></td><td>therapeutic generic</td><td>**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n * Ranitidine for cimetidine</td><td>23106</td><td/><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\"> F<a name=\"v3-substanceAdminSubstitution-F\"> </a></td><td>formulary</td><td>**Description:** This substitution was performed or is permitted based on formulary guidelines.</td><td>16625</td><td/><td>active</td></tr><tr><td>2</td><td style=\"white-space:nowrap\"> N<a name=\"v3-substanceAdminSubstitution-N\"> </a></td><td>none</td><td>No substitution occurred or is permitted.</td><td>16622</td><td/><td>active</td></tr></table></div>" }, "url" : "http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution", "identifier" : [ { "system" : "urn:ietf:rfc:3986", "value" : "urn:oid:2.16.840.1.113883.5.1070" } ], "version" : "2.0.0", "name" : "SubstanceAdminSubstitution", "title" : "Substance Admin Substitution", "status" : "active", "date" : "2019-03-20T00:00:00-04:00", "publisher" : "Health Level 7", "contact" : [ { "name" : "Health Level Seven" } ], "description" : "Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.", "hierarchyMeaning" : "is-a", "content" : "complete", "property" : [ { "extension" : [ { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry", "valueCode" : "antisymmetric" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity", "valueCode" : "transitive" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity", "valueCode" : "irreflexive" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable", "valueBoolean" : true }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind", "valueCode" : "Specializes" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName", "valueString" : "Generalizes" } ], "code" : "Specializes", "description" : "The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.", "type" : "Coding" }, { "extension" : [ { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry", "valueCode" : "antisymmetric" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity", "valueCode" : "transitive" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity", "valueCode" : "irreflexive" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable", "valueBoolean" : true }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind", "valueCode" : "Generalizes" }, { "url" : "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName", "valueString" : "Specializes" } ], "code" : "Generalizes", "description" : "Inverse of Specializes. Only included as a derived relationship.", "type" : "Coding" }, { "code" : "internalId", "uri" : "http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id", "description" : "The internal identifier for the concept in the HL7 Access database repository.", "type" : "code" }, { "code" : "notSelectable", "uri" : "http://hl7.org/fhir/concept-properties#notSelectable", "description" : "Indicates that the code is abstract - only intended to be used as a selector for other concepts", "type" : "boolean" }, { "code" : "status", "uri" : "http://hl7.org/fhir/concept-properties#status", "description" : "Designation of a concept's state. Normally is not populated unless the state is retired.", "type" : "code" } ], "concept" : [ { "code" : "_ActSubstanceAdminSubstitutionCode", "display" : "ActSubstanceAdminSubstitutionCode", "definition" : "**Description:** Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.", "property" : [ { "code" : "notSelectable", "valueBoolean" : true }, { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "21284" } ], "concept" : [ { "code" : "E", "display" : "equivalent", "definition" : "**Description:** Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "23107" } ], "concept" : [ { "code" : "EC", "display" : "equivalent composition", "definition" : "**Description:** \r\n\r\nSubstitution occurred or is permitted with another product that is a:\r\n\r\n * pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n * pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n * *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n * *Pharmaceutical equivalent:* Lisonpril for Zestril", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "23108" } ], "concept" : [ { "code" : "BC", "display" : "brand composition", "definition" : "**Description:** \r\n\r\nSubstitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n * Zestril for Prinivil\r\n * Coumadin for Jantoven", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "23109" } ] }, { "code" : "G", "display" : "generic composition", "definition" : "**Description:** Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n * Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "16623" } ] } ] }, { "code" : "TE", "display" : "therapeutic alternative", "definition" : "**Description:** Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n * ranitidine for Tagamet", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "16624" } ], "concept" : [ { "code" : "TB", "display" : "therapeutic brand", "definition" : "**Description:** Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n * Zantac for Tagamet", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "23105" } ] }, { "code" : "TG", "display" : "therapeutic generic", "definition" : "**Description:** Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n * Ranitidine for cimetidine", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "23106" } ] } ] } ] }, { "code" : "F", "display" : "formulary", "definition" : "**Description:** This substitution was performed or is permitted based on formulary guidelines.", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "16625" } ] }, { "code" : "N", "display" : "none", "definition" : "No substitution occurred or is permitted.", "property" : [ { "code" : "status", "valueCode" : "active" }, { "code" : "internalId", "valueCode" : "16622" } ] } ] } ] }