v3-ObservationInterpretation
type: CodeSystem
node role: treeRoot
resource.id:
  value: v3-ObservationInterpretation
resource.language:
  value: en
domain resource.text:
  narrative.status:
    value: extensions
  narrative.div: ObservationInterpretation One or more codes providing a rough qualitative interpretation of the observation, such as "normal" / "abnormal", "low" / "high", "better" / "worse", "resistant" / "susceptible", "expected" / "not expected". The value set is intended to be for ANY use where coded representation of an interpretation is needed. Properties Code URL Description Type Specializes The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric. Coding Generalizes Inverse of Specializes. Only included as a derived relationship. Coding internalId http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id The internal identifier for the concept in the HL7 Access database repository. code notSelectable http://hl7.org/fhir/concept-properties#notSelectable Indicates that the code is abstract - only intended to be used as a selector for other concepts boolean status http://hl7.org/fhir/concept-properties#status A property that indicates the status of the concept. One of active, experimental, deprecated, or retired. code deprecationDate http://hl7.org/fhir/concept-properties#deprecationDate The date at which a concept was deprecated. Concepts that are deprecated but not inactive can still be used, but their use is discouraged. dateTime subsumedBy http://hl7.org/fhir/concept-properties#parent The concept code of a parent concept code This code system http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation defines the following codes: Lvl Code Display Definition Deprecated internalId Not Selectable status deprecationDate Parent 1 _GeneticObservationInterpretation GeneticObservationInterpretation Codes that specify interpretation of genetic analysis, such as "positive", "negative", "carrier", "responsive", etc. 22646 true active 2 CAR Carrier The patient is considered as carrier …
code system.url:
  value: http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation
code system.identifier:
  index: 0
  identifier.system:
    value: urn:ietf:rfc:3986
  identifier.value:
    value: urn:oid:2.16.840.1.113883.5.83
code system.version:
  value: 2.0.0
code system.name:
  value: ObservationInterpretation
code system.title:
  value: ObservationInterpretation
code system.status:
  value: active
code system.date:
  value: 2019-03-20T00:00:00-04:00
code system.publisher:
  value: Health Level 7
code system.contact:
  index: 0
  contact detail.name:
    value: Health Level Seven
code system.description:
  value: One or more codes providing a rough qualitative interpretation of the observation, such as "normal" / "abnormal", "low" / "high", "better" / "worse", "resistant" / "susceptible", "expected" / "not expected". The value set is intended to be for ANY use where coded representation of an interpretation is needed.
code system.hierarchy meaning:
  value: is-a
code system.content:
  value: complete
code system.property:
  index: 0
  element.extension:
    index: 0
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry
    extension.value code:
      value: antisymmetric
  element.extension:
    index: 1
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity
    extension.value code:
      value: transitive
  element.extension:
    index: 2
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity
    extension.value code:
      value: irreflexive
  element.extension:
    index: 3
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable
    extension.value boolean:
      value: true
  element.extension:
    index: 4
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind
    extension.value code:
      value: Specializes
  element.extension:
    index: 5
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName
    extension.value string:
      value: Generalizes
  code system.property.code:
    value: Specializes
  code system.property.description:
    value: The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.
  code system.property.type:
    value: Coding
code system.property:
  index: 1
  element.extension:
    index: 0
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry
    extension.value code:
      value: antisymmetric
  element.extension:
    index: 1
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity
    extension.value code:
      value: transitive
  element.extension:
    index: 2
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity
    extension.value code:
      value: irreflexive
  element.extension:
    index: 3
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable
    extension.value boolean:
      value: true
  element.extension:
    index: 4
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind
    extension.value code:
      value: Generalizes
  element.extension:
    index: 5
    extension.url:
      value: http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName
    extension.value string:
      value: Specializes
  code system.property.code:
    value: Generalizes
  code system.property.description:
    value: Inverse of Specializes. Only included as a derived relationship.
  code system.property.type:
    value: Coding
code system.property:
  index: 2
  code system.property.code:
    value: internalId
  code system.property.uri:
    value: http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id
  code system.property.description:
    value: The internal identifier for the concept in the HL7 Access database repository.
  code system.property.type:
    value: code
code system.property:
  index: 3
  code system.property.code:
    value: notSelectable
  code system.property.uri:
    value: http://hl7.org/fhir/concept-properties#notSelectable
  code system.property.description:
    value: Indicates that the code is abstract - only intended to be used as a selector for other concepts
  code system.property.type:
    value: boolean
code system.property:
  index: 4
  code system.property.code:
    value: status
  code system.property.uri:
    value: http://hl7.org/fhir/concept-properties#status
  code system.property.description:
    value: A property that indicates the status of the concept. One of active, experimental, deprecated, or retired.
  code system.property.type:
    value: code
code system.property:
  index: 5
  code system.property.code:
    value: deprecationDate
  code system.property.uri:
    value: http://hl7.org/fhir/concept-properties#deprecationDate
  code system.property.description:
    value: The date at which a concept was deprecated. Concepts that are deprecated but not inactive can still be used, but their use is discouraged.
  code system.property.type:
    value: dateTime
code system.property:
  index: 6
  code system.property.code:
    value: subsumedBy
  code system.property.uri:
    value: http://hl7.org/fhir/concept-properties#parent
  code system.property.description:
    value: The concept code of a parent concept
  code system.property.type:
    value: code
code system.concept:
  index: 0
  code system.concept.code:
    value: _GeneticObservationInterpretation
  code system.concept.display:
    value: GeneticObservationInterpretation
  code system.concept.definition:
    value: Codes that specify interpretation of genetic analysis, such as "positive", "negative", "carrier", "responsive", etc.
  code system.concept.property:
    index: 0
    code system.concept.property.code:
      value: notSelectable
    code system.concept.property.value boolean:
      value: true
  code system.concept.property:
    index: 1
    code system.concept.property.code:
      value: status
    code system.concept.property.value code:
      value: active
  code system.concept.property:
    index: 2
    code system.concept.property.code:
      value: internalId

value: 22646

index: 1
code system.concept.code:
  value: _ObservationInterpretationChange
code system.concept.display:
  value: ObservationInterpretationChange
code system.concept.definition:
  value: Interpretations of change of quantity and/or severity. At most one of B or W and one of U or D allowed.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21090

index: 2
code system.concept.code:
  value: _ObservationInterpretationExceptions
code system.concept.display:
  value: ObservationInterpretationExceptions
code system.concept.definition:
  value: Technical exceptions resulting in the inability to provide an interpretation. At most one allowed. Does not imply normality or severity.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21091

index: 3
code system.concept.code:
  value: _ObservationInterpretationNormality
code system.concept.display:
  value: ObservationInterpretationNormality
code system.concept.definition:
  value: Interpretation of normality or degree of abnormality (including critical or "alert" level). Concepts in this category are mutually exclusive, i.e., at most one is allowed.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21092

index: 4
code system.concept.code:
  value: _ObservationInterpretationSusceptibility
code system.concept.display:
  value: ObservationInterpretationSusceptibility
code system.concept.definition:
  value: Interpretations of anti-microbial susceptibility testing results (microbiology). At most one allowed.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21093

index: 5
code system.concept.code:
  value: EX
code system.concept.display:
  value: outside threshold
code system.concept.definition:
  value: The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported. **Example:** A positive result on a Hepatitis screening test. *Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal "030103C\_VOCAB\_RCRIM\_l\_quade\_RCRIM Obs Interp\_20051028154455". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21634

index: 6
code system.concept.code:
  value: HM
code system.concept.display:
  value: Hold for Medical Review
code system.concept.definition:
  value: Hold for Medical Review *Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 "Interpretation Codes."
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2016-11-10T00:00:00-05:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23790

index: 7
code system.concept.code:
  value: ObservationInterpretationDetection
code system.concept.display:
  value: ObservationInterpretationDetection
code system.concept.definition:
  value: Interpretations of the presence or absence of a component / analyte or organism in a test or of a sign in a clinical observation. In keeping with laboratory data processing practice, these concepts provide a categorical interpretation of the "meaning" of the quantitative value for the same observation.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 22805

index: 8
code system.concept.code:
  value: ObservationInterpretationExpectation
code system.concept.display:
  value: ObservationInterpretationExpectation
code system.concept.definition:
  value: Interpretation of the observed result taking into account additional information (contraindicators) about the patient's situation. Concepts in this category are mutually exclusive, i.e., at most one is allowed.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23723

index: 9
code system.concept.code:
  value: OBX
code system.concept.display:
  value: Interpretation qualifiers in separate OBX segments
code system.concept.definition:
  value: Interpretation qualifiers in separate OBX segments *Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 "Interpretation Codes."
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2016-11-10T00:00:00-05:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23789

index: 10
code system.concept.code:
  value: ReactivityObservationInterpretation
code system.concept.display:
  value: ReactivityObservationInterpretation
code system.concept.definition:
  value: Interpretations of the presence and level of reactivity of the specified component / analyte with the reagent in the performed laboratory test.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: notSelectable
  code system.concept.property.value boolean:
    value: true
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23568

index: 11
code system.concept.code:
  value: CAR
code system.concept.display:
  value: Carrier
code system.concept.definition:
  value: The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23559
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _GeneticObservationInterpretation

index: 12
code system.concept.code:
  value: Carrier
code system.concept.display:
  value: Carrier
code system.concept.definition:
  value: The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder. ***Deprecation Comment:*** This code is currently the same string as the print name for this concept and is inconsistent with the conventions being used for the other codes in the coding system, as it is a full word with initial capitalization, rather than an all upper case mnemonic. The recommendation from OO is to deprecate the code "Carrier" and to add "CAR" as the new active code representation for this concept.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2013-07-28T00:00:00-04:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 22647
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _GeneticObservationInterpretation

index: 13
code system.concept.code:
  value: B
code system.concept.display:
  value: Better
code system.concept.definition:
  value: The current result or observation value has improved compared to the previous result or observation value (the change is significant as defined in the respective test procedure). \[Note: This can be applied to quantitative or qualitative observations.\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10215
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationChange

index: 14
code system.concept.code:
  value: D
code system.concept.display:
  value: Significant change down
code system.concept.definition:
  value: The current result has decreased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10218
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationChange

index: 15
code system.concept.code:
  value: U
code system.concept.display:
  value: Significant change up
code system.concept.definition:
  value: The current result has increased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10217
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationChange

index: 16
code system.concept.code:
  value: W
code system.concept.display:
  value: Worse
code system.concept.definition:
  value: The current result or observation value has degraded compared to the previous result or observation value (the change is significant as defined in the respective test procedure). \[Note: This can be applied to quantitative or qualitative observations.\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10216
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationChange

index: 17
code system.concept.code:
  value: <
code system.concept.display:
  value: Off scale low
code system.concept.definition:
  value: The result is below the minimum detection limit (the test procedure or equipment is the limiting factor). Synonyms: Below analytical limit, low off scale.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10226
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationExceptions

index: 18
code system.concept.code:
  value: >
code system.concept.display:
  value: Off scale high
code system.concept.definition:
  value: The result is above the maximum quantifiable limit (the test procedure or equipment is the limiting factor). Synonyms: Above analytical limit, high off scale.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10227
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationExceptions

index: 19
code system.concept.code:
  value: AC
code system.concept.display:
  value: Anti-complementary substances present
code system.concept.definition:
  value: A valid result cannot be obtained for the specified component / analyte due to the presence of anti-complementary substances in the sample. ***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 "Interpretation Codes.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2016-11-10T00:00:00-05:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23564
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationExceptions

index: 20
code system.concept.code:
  value: IE
code system.concept.display:
  value: Insufficient evidence
code system.concept.definition:
  value: There is insufficient evidence that the species in question is a good target for therapy with the drug. A categorical interpretation is not possible. \[Note: A MIC with "IE" and/or a comment may be reported (without an accompanying S, I or R-categorization).\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23567
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationExceptions
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 21
code system.concept.code:
  value: QCF
code system.concept.display:
  value: Quality control failure
code system.concept.definition:
  value: A result cannot be considered valid for the specified component / analyte or organism due to failure in the quality control testing component. ***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 "Interpretation Codes.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2016-11-10T00:00:00-05:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23565
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationExceptions

index: 22
code system.concept.code:
  value: TOX
code system.concept.display:
  value: Cytotoxic substance present
code system.concept.definition:
  value: A valid result cannot be obtained for the specified organism or cell line due to the presence of cytotoxic substances in the sample or culture. ***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 "Interpretation Codes.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2016-11-10T00:00:00-05:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23566
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationExceptions

index: 23
code system.concept.code:
  value: A
code system.concept.display:
  value: Abnormal
code system.concept.definition:
  value: The result or observation value is outside the reference range or expected norm (as defined for the respective test procedure). \[Note: Typically applies to non-numeric results.\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10208
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationNormality

index: 24
code system.concept.code:
  value: N
code system.concept.display:
  value: Normal
code system.concept.definition:
  value: The result or observation value is within the reference range or expected norm (as defined for the respective test procedure). \[Note: Applies to numeric or non-numeric results.\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10207
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationNormality

index: 25
code system.concept.code:
  value: I
code system.concept.display:
  value: Intermediate
code system.concept.definition:
  value: Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2 \[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\] \[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\] \[Note 3: This class also indicates a "buffer zone," to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\] \[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10221
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 26
code system.concept.code:
  value: MS
code system.concept.display:
  value: moderately susceptible
code system.concept.definition:
  value: The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder. ***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2013-07-28T00:00:00-04:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10222
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 27
code system.concept.code:
  value: NCL
code system.concept.display:
  value: No CLSI defined breakpoint
code system.concept.definition:
  value: Use when not enough clinical trial data published by the Clinical and Laboratory Standards Institutes (CLSI) is available to establish the breakpoints for susceptible / intermediate and resistant.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23886
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 28
code system.concept.code:
  value: NS
code system.concept.display:
  value: Non-susceptible
code system.concept.definition:
  value: A category used for isolates for which only a susceptible interpretive criterion has been designated because of the absence or rare occurrence of resistant strains. Isolates that have MICs above or zone diameters below the value indicated for the susceptible breakpoint should be reported as non-susceptible. NOTE 1: An isolate that is interpreted as non-susceptible does not necessarily mean that the isolate has a resistance mechanism. It is possible that isolates with MICs above the susceptible breakpoint that lack resistance mechanisms may be encountered within the wild-type distribution subsequent to the time the susceptible-only breakpoint is set. NOTE 2: For strains yielding results in the "nonsusceptible" category, organism identification and antimicrobial susceptibility test results should be confirmed. Synonym: decreased susceptibility.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23557
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 29
code system.concept.code:
  value: R
code system.concept.display:
  value: Resistant
code system.concept.definition:
  value: Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic failure. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2 \[Note 1: Bacterial strains are categorized as resistant by applying the appropriate breakpoints in a defined phenotypic test system.\] \[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10220
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 30
code system.concept.code:
  value: S
code system.concept.display:
  value: Susceptible
code system.concept.definition:
  value: Bacterial strain inhibited by in vitro concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic success. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\_Terminolo.htm) Synonym (earlier term): Sensitive Projects: ISO 20776-1, ISO 20776-2 \[Note 1: Bacterial strains are categorized as susceptible by applying the appropriate breakpoints in a defined phenotypic system.\] \[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10223
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 31
code system.concept.code:
  value: VS
code system.concept.display:
  value: very susceptible
code system.concept.definition:
  value: The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder. ***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2013-07-28T00:00:00-04:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10224
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: _ObservationInterpretationSusceptibility

index: 32
code system.concept.code:
  value: AA
code system.concept.display:
  value: Critical abnormal
code system.concept.definition:
  value: The result or observation value is outside a reference range or expected norm at a level at which immediate action should be considered for patient safety (as defined for the respective test procedure). \[Note: Typically applies to non-numeric results. Analogous to critical/panic limits for numeric results.\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10211
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: A

index: 33
code system.concept.code:
  value: H
code system.concept.display:
  value: High
code system.concept.definition:
  value: The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure). Synonym: Above high normal
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10210
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: A

index: 34
code system.concept.code:
  value: L
code system.concept.display:
  value: Low
code system.concept.definition:
  value: The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure). Synonym: Below low normal
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10209
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: A

index: 35
code system.concept.code:
  value: HH
code system.concept.display:
  value: Critical high
code system.concept.definition:
  value: The result for a quantitative observation is above a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure). Synonym: Above upper panic limits.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10213
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: AA
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: H>
code system.concept.property:
  index: 4
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: HU

index: 36
code system.concept.code:
  value: LL
code system.concept.display:
  value: Critical low
code system.concept.definition:
  value: The result for a quantitative observation is below a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure). Synonym: Below lower panic limits.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 10212
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: AA
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: L<
code system.concept.property:
  index: 4
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: LU

index: 37
code system.concept.code:
  value: HX
code system.concept.display:
  value: above high threshold
code system.concept.definition:
  value: The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported. **Example:** A positive result on a Hepatitis screening test. *Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal "030103C\_VOCAB\_RCRIM\_l\_quade\_RCRIM Obs Interp\_20051028154455". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21636
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: EX

index: 38
code system.concept.code:
  value: LX
code system.concept.display:
  value: below low threshold
code system.concept.definition:
  value: The numeric observation/test result is interpreted as being below the low threshold value for a particular protocol within which the result is being reported. **Example:** A Total White Blood Cell Count falling below a protocol-defined threshold value of 3000/mm^3 *Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal "030103C\_VOCAB\_RCRIM\_l\_quade\_RCRIM Obs Interp\_20051028154455". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 21635
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: EX

index: 39
code system.concept.code:
  value: H>
code system.concept.display:
  value: Significantly high
code system.concept.definition:
  value: A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician. \[Note: This level is situated between 'H' and 'HH'.\] *Deprecation Comment:* The code 'H>' is being deprecated in order to align with the use of the code 'HU' for "Very high" in V2 Table 0078 "Interpretation Codes". \[Note: The use of code 'H>' is non-preferred, as this code is deprecated and on track to be retired; use code 'HU' instead.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2015-03-23T00:00:00-04:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23560
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: H

index: 40
code system.concept.code:
  value: HU
code system.concept.display:
  value: Significantly high
code system.concept.definition:
  value: A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23742
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: H

index: 41
code system.concept.code:
  value: E
code system.concept.display:
  value: Equivocal
code system.concept.definition:
  value: The test or procedure was successfully performed, but the results are borderline and can neither be declared positive / negative nor detected / not detected according to the current established criteria.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23732
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: IND

index: 42
code system.concept.code:
  value: L<
code system.concept.display:
  value: Significantly low
code system.concept.definition:
  value: A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician. \[Note: This level is situated between 'L' and 'LL'.\] *Deprecation Comment:* The code 'L<' is being deprecated in order to align with the use of the code 'LU' for "Very low" in V2 Table 0078 "Interpretation Codes". \[Note: The use of code 'L<' is non-preferred, as this code is deprecated and on track to be retired; use code 'LU' instead.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: deprecated
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: deprecationDate
  code system.concept.property.value date time:
    value: 2015-03-23T00:00:00-04:00
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23561
code system.concept.property:
  index: 3
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: L

index: 43
code system.concept.code:
  value: LU
code system.concept.display:
  value: Significantly low
code system.concept.definition:
  value: A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23743
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: L

index: 44
code system.concept.code:
  value: ND
code system.concept.display:
  value: Not detected
code system.concept.definition:
  value: The presence of the specified component / analyte, organism or clinical sign could not be determined within the limit of detection of the performed test or procedure.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23563
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: NEG

index: 45
code system.concept.code:
  value: IND
code system.concept.display:
  value: Indeterminate
code system.concept.definition:
  value: The specified component / analyte, organism or clinical sign could neither be declared positive / negative nor detected / not detected by the performed test or procedure. *Usage Note:* For example, if the specimen was degraded, poorly processed, or was missing the required anatomic structures, then "indeterminate" (i.e. "cannot be determined") is the appropriate response, not "equivocal".
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 22807
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ObservationInterpretationDetection

index: 46
code system.concept.code:
  value: NEG
code system.concept.display:
  value: Negative
code system.concept.definition:
  value: An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure. \[Note: Negative does not necessarily imply the complete absence of the specified item.\]
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 22808
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ObservationInterpretationDetection

index: 47
code system.concept.code:
  value: POS
code system.concept.display:
  value: Positive
code system.concept.definition:
  value: A presence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 22806
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ObservationInterpretationDetection

index: 48
code system.concept.code:
  value: EXP
code system.concept.display:
  value: Expected
code system.concept.definition:
  value: This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be "Expected" (e.g., presence of drugs in a patient that is taking prescription medication for pain management).
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23724
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ObservationInterpretationExpectation

index: 49
code system.concept.code:
  value: UNE
code system.concept.display:
  value: Unexpected
code system.concept.definition:
  value: This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be "Unexpected" (e.g., presence of non-prescribed drugs in a patient that is taking prescription medication for pain management).
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23725
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ObservationInterpretationExpectation

index: 50
code system.concept.code:
  value: DET
code system.concept.display:
  value: Detected
code system.concept.definition:
  value: The measurement of the specified component / analyte, organism or clinical sign above the limit of detection of the performed test or procedure.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23562
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: POS

index: 51
code system.concept.code:
  value: SYN-R
code system.concept.display:
  value: Synergy - resistant
code system.concept.definition:
  value: A category for isolates where the bacteria (e.g. enterococci) are not susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will not be effective. *Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside. *Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23621
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: R

index: 52
code system.concept.code:
  value: NR
code system.concept.display:
  value: Non-reactive
code system.concept.definition:
  value: An absence finding used to indicate that the specified component / analyte did not react measurably with the reagent.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23569
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ReactivityObservationInterpretation

index: 53
code system.concept.code:
  value: RR
code system.concept.display:
  value: Reactive
code system.concept.definition:
  value: A presence finding used to indicate that the specified component / analyte reacted with the reagent above the reliably measurable limit of the performed test.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23570
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: ReactivityObservationInterpretation

index: 54
code system.concept.code:
  value: WR
code system.concept.display:
  value: Weakly reactive
code system.concept.definition:
  value: A weighted presence finding used to indicate that the specified component / analyte reacted with the reagent, but below the reliably measurable limit of the performed test.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23571
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: RR

index: 55
code system.concept.code:
  value: SDD
code system.concept.display:
  value: Susceptible-dose dependent
code system.concept.definition:
  value: A category that includes isolates with antimicrobial agent minimum inhibitory concentrations (MICs) that approach usually attainable blood and tissue levels and for which response rates may be lower than for susceptible isolates. Reference: CLSI document M44-A2 2009 "Method for antifungal disk diffusion susceptibility testing of yeasts; approved guideline - second edition" - page 2.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23558
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: S

index: 56
code system.concept.code:
  value: SYN-S
code system.concept.display:
  value: Synergy - susceptible
code system.concept.definition:
  value: A category for isolates where the bacteria (e.g. enterococci) are susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will be effective. *Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside. *Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.
code system.concept.property:
  index: 0
  code system.concept.property.code:
    value: status
  code system.concept.property.value code:
    value: active
code system.concept.property:
  index: 1
  code system.concept.property.code:
    value: internalId
  code system.concept.property.value code:
    value: 23620
code system.concept.property:
  index: 2
  code system.concept.property.code:
    value: subsumedBy
  code system.concept.property.value code:
    value: S