@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess> a fhir:CodeSystem;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "adverse-event-causality-assess"];
  fhir:Resource.meta [
     fhir:Meta.lastUpdated [ fhir:value "2020-04-09T21:10:28.568+00:00"^^xsd:dateTime ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n            \n      <h2>AdverseEventCausalityAssessment</h2>\n            \n      <div>\n              \n        <p>Codes for the assessment of whether the entity caused the event.</p>\n\n            \n      </div>\n            \n      <p>This code system http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess defines the following codes:</p>\n            \n      <table class=\"codes\">\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">\n                  \n            <b>Code</b>\n                \n          </td>\n                \n          <td>\n                  \n            <b>Display</b>\n                \n          </td>\n                \n          <td>\n                  \n            <b>Definition</b>\n                \n          </td>\n              \n        </tr>\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">certain\n                  \n            <a name=\"adverse-event-causality-assess-certain\"> </a>\n                \n          </td>\n                \n          <td>Certain</td>\n                \n          <td>i) Event or laboratory test abnormality, with plausible time relationship to drug intake; ii) Cannot be explained by disease or other drugs; iii) Response to withdrawal plausible (pharmacologically, pathologically); iv) Event definitive pharmacologically or phenomenologically (i.e. an objective and specific medical disorder or a recognized pharmacological phenomenon); or v) Re-challenge satisfactory, if necessary.</td>\n              \n        </tr>\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">probably-likely\n                  \n            <a name=\"adverse-event-causality-assess-probably-likely\"> </a>\n                \n          </td>\n                \n          <td>Probably/Likely</td>\n                \n          <td>i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Unlikely to be attributed to disease or other drugs; iii) Response to withdrawal clinically reasonable; or iv) Re-challenge not required.</td>\n              \n        </tr>\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">possible\n                  \n            <a name=\"adverse-event-causality-assess-possible\"> </a>\n                \n          </td>\n                \n          <td>Possible</td>\n                \n          <td>i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Could also be explained by disease or other drugs; or iii) Information on drug withdrawal may be lacking or unclear.</td>\n              \n        </tr>\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">unlikely\n                  \n            <a name=\"adverse-event-causality-assess-unlikely\"> </a>\n                \n          </td>\n                \n          <td>Unlikely</td>\n                \n          <td>i) Event or laboratory test abnormality, with a time to drug intake that makes a relationship improbable (but not impossible); or ii) Disease or other drugs provide plausible explanations.</td>\n              \n        </tr>\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">conditional-classified\n                  \n            <a name=\"adverse-event-causality-assess-conditional-classified\"> </a>\n                \n          </td>\n                \n          <td>Conditional/Classified</td>\n                \n          <td>i) Event or laboratory test abnormality; ii) More data for proper assessment needed; or iii) Additional data under examination.</td>\n              \n        </tr>\n              \n        <tr>\n                \n          <td style=\"white-space:nowrap\">unassessable-unclassifiable\n                  \n            <a name=\"adverse-event-causality-assess-unassessable-unclassifiable\"> </a>\n                \n          </td>\n                \n          <td>Unassessable/Unclassifiable</td>\n                \n          <td>i) Report suggesting an adverse reaction; ii) Cannot be judged because information is insufficient or contradictory; or iii) Data cannot be supplemented or verified.</td>\n              \n        </tr>\n            \n      </table>\n          \n    </div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg" ];
     fhir:Extension.valueCode [ fhir:value "pc" ]
  ], [
     fhir:index 1;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status" ];
     fhir:Extension.valueCode [ fhir:value "draft" ]
  ], [
     fhir:index 2;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm" ];
     fhir:Extension.valueInteger [ fhir:value "1"^^xsd:integer ]
  ];
  fhir:CodeSystem.url [ fhir:value "http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess"];
  fhir:CodeSystem.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "urn:ietf:rfc:3986" ];
     fhir:Identifier.value [ fhir:value "urn:oid:2.16.840.1.113883.4.642.1.1254" ]
  ];
  fhir:CodeSystem.version [ fhir:value "4.2.0"];
  fhir:CodeSystem.name [ fhir:value "AdverseEventCausalityAssessment"];
  fhir:CodeSystem.title [ fhir:value "AdverseEventCausalityAssessment"];
  fhir:CodeSystem.status [ fhir:value "draft"];
  fhir:CodeSystem.experimental [ fhir:value "false"^^xsd:boolean];
  fhir:CodeSystem.date [ fhir:value "2020-04-09T21:10:28+00:00"^^xsd:dateTime];
  fhir:CodeSystem.publisher [ fhir:value "HL7 (FHIR Project)"];
  fhir:CodeSystem.contact [
     fhir:index 0;
     fhir:ContactDetail.telecom [
       fhir:index 0;
       fhir:ContactPoint.system [ fhir:value "url" ];
       fhir:ContactPoint.value [ fhir:value "http://hl7.org/fhir" ]
     ], [
       fhir:index 1;
       fhir:ContactPoint.system [ fhir:value "email" ];
       fhir:ContactPoint.value [ fhir:value "fhir@lists.hl7.org" ]
     ]
  ];
  fhir:CodeSystem.description [ fhir:value "Codes for the assessment of whether the entity caused the event."];
  fhir:CodeSystem.caseSensitive [ fhir:value "true"^^xsd:boolean];
  fhir:CodeSystem.valueSet [
     fhir:value "http://terminology.hl7.org/ValueSet/adverse-event-causality-assess";
     fhir:link <http://terminology.hl7.org/ValueSet/adverse-event-causality-assess>
  ];
  fhir:CodeSystem.content [ fhir:value "complete"];
  fhir:CodeSystem.concept [
     fhir:index 0;
     fhir:CodeSystem.concept.code [ fhir:value "certain" ];
     fhir:CodeSystem.concept.display [ fhir:value "Certain" ];
     fhir:CodeSystem.concept.definition [ fhir:value "i) Event or laboratory test abnormality, with plausible time relationship to drug intake; ii) Cannot be explained by disease or other drugs; iii) Response to withdrawal plausible (pharmacologically, pathologically); iv) Event definitive pharmacologically or phenomenologically (i.e. an objective and specific medical disorder or a recognized pharmacological phenomenon); or v) Re-challenge satisfactory, if necessary." ]
  ], [
     fhir:index 1;
     fhir:CodeSystem.concept.code [ fhir:value "probably-likely" ];
     fhir:CodeSystem.concept.display [ fhir:value "Probably/Likely" ];
     fhir:CodeSystem.concept.definition [ fhir:value "i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Unlikely to be attributed to disease or other drugs; iii) Response to withdrawal clinically reasonable; or iv) Re-challenge not required." ]
  ], [
     fhir:index 2;
     fhir:CodeSystem.concept.code [ fhir:value "possible" ];
     fhir:CodeSystem.concept.display [ fhir:value "Possible" ];
     fhir:CodeSystem.concept.definition [ fhir:value "i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Could also be explained by disease or other drugs; or iii) Information on drug withdrawal may be lacking or unclear." ]
  ], [
     fhir:index 3;
     fhir:CodeSystem.concept.code [ fhir:value "unlikely" ];
     fhir:CodeSystem.concept.display [ fhir:value "Unlikely" ];
     fhir:CodeSystem.concept.definition [ fhir:value "i) Event or laboratory test abnormality, with a time to drug intake that makes a relationship improbable (but not impossible); or ii) Disease or other drugs provide plausible explanations." ]
  ], [
     fhir:index 4;
     fhir:CodeSystem.concept.code [ fhir:value "conditional-classified" ];
     fhir:CodeSystem.concept.display [ fhir:value "Conditional/Classified" ];
     fhir:CodeSystem.concept.definition [ fhir:value "i) Event or laboratory test abnormality; ii) More data for proper assessment needed; or iii) Additional data under examination." ]
  ], [
     fhir:index 5;
     fhir:CodeSystem.concept.code [ fhir:value "unassessable-unclassifiable" ];
     fhir:CodeSystem.concept.display [ fhir:value "Unassessable/Unclassifiable" ];
     fhir:CodeSystem.concept.definition [ fhir:value "i) Report suggesting an adverse reaction; ii) Cannot be judged because information is insufficient or contradictory; or iii) Data cannot be supplemented or verified." ]
  ] .

# - ontology header ------------------------------------------------------------

<http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess.ttl> a owl:Ontology;
  owl:imports fhir:fhir.ttl .

# -------------------------------------------------------------------------------------